Beating Fibromyalgia?

I was directed to a link to a documentary by producers Living Whole Body Health and Dr. Tim Weeks called Beating Fibromyalgia

This documentary focuses on the life of Prasad Moss, a 37 years old man who has suffered from Fibromyalgia for over 20 years causing him great pain and disabilities. This 61 minutes long documentary shows Dr. Tim Weeks and Prasad Moss take up a 21-day intensive natural healing protocol to help Prasad find relief from his pain and fatigue, and after the 21 days Prasad becomes pain-free.

This film is available on Amazon Prime Video and can be viewed for free by Amazon Prime Members. It can also be rented for as low as $0.99 for those who don’t have an Amazon Prime membership. (This is NOT me advertising or endorsing this film as) it seems that it cannot be viewed in my area (Melbourne, Australia) so I can’t review it.

I’d love to hear some of your (objective) opinions below.

 

If You Poison Us, Do We Not Die?

industries_health_research and development_ Tarantula venom could provide relief from Irritable Bowel Syndrome_bannerTARANTULA venom is being used to help develop pain relief medications for people suffering from Irritable Bowel Syndrome.

Researchers from The University of Adelaide in South Australia found that a specific peptide in the spider venom could be used to understand how people sense pain. Two toxins were found to specifically target Nav 1.1, a voltage-gated sodium channel in the nervous system to initiate the electrical impulses that signal pain.

Associate Professor Stuart Brierley said the study demonstrated that Nav 1.1 contributed to mechanical, but not thermal, pain signalling.

“Using the highly specific peptide in the spider toxin we were able to work out how pain nerve fibres signal in a healthy situation and also in chronic abdominal pain such as what you see in Irritable Bowel Syndrome (IBS),” Assoc Prof Brierley said.

“We found that the spider toxin was able to cause a lot more pain in the IBS state than what it was in the healthy state. It’s important to note that because of the studies we should be able to develop treatments for IBS based pain – blockers for Nav 1.1 that only target the peripheral and don’t go to the central nervous system.”

106. cure #1

The causes of IBS are still unknown but it affects about 10 per cent of people globally (and lots of FMS patients). Chronic abdominal pain is the predominant symptom of IBS.

Assoc Prof Brierley said that until recently there had not been much research into the role of the Nav 1.1 channel subtype on the peripheral nervous system.

“Over a long period of time we were able to work out that one particular compound was in the venom that you could isolate, separate out and acted on this Nav 1.1 channel,” he said. “It gave us a highly specific and highly selective tool to look at its role in pain.”

Many nociceptors or pain sensing nerve fibres use Nav channels to initiate the electrical impulses that signal pain. Although the study focused on the peripheral nervous system, the findings also pose potential implications for central nervous system diseases such as epilepsy (and FMS)

The study was a collaboration between the University of Adelaide, Flinders University, South Australian Health and Medical Research Institute (SAHMRI), the University of Queensland, The University of California, John Hopkins University and the Medical College of Wisconsin. It was published in Nature last week.

take it

Tank You, #Fibro

So I read this in News For America

Amazing news!

(for now…)

Fibromyalgia has, throughout history, been incredibly difficult to identify and diagnose because it appears, at first glance, to be something else since its symptoms, which include musculoskeletal pain, fatigue, mood swings, and memory loss, are fairly common.

To provide some perspective 1 in 70 people, mostly women, in the United States actually have fibromyalgia.

There is amazing news though, hyperbaric oxygen treatment has made some game changing progress in medicine for those who have this horrible condition. Researchers from Tel Aviv University found that women who tried hyperbaric oxygen treatments were able to reduce or entirely eliminate  their need for pain medication.

Researchers believe that the primary cause of fibromyalgia is a disruption of brain mechanisms that are responsible for processing pain;

“As a physician, the most important finding for me is that 70 percent of the patients could recover from their fibromyalgia symptoms. The most exciting finding for the world of research, however, is that we were able to map the malfunctioning brain regions responsible for the syndrome… The intake of [the pain medication they were taking] eased the pain but did not reverse the condition. But hyperbaric oxygen treatments did reverse the condition… Hyperbaric oxygen treatments are designed to address the actual cause of fibromyalgia – the brain pathology responsible for the syndrome. 

As you can see this is extraordinary news.

Dr No (or Not Yet)

A resourceful Australian agent seeks the cure to the persistent symptoms of Fibromyalgia (…and the disruption of the American space program!)Dr No

I’m part of the study!…Not sure what part, though.

No longer is Lyrica, Voltaren, Tramadol, Endone or anything stronger than Panadol living in my pill organiser. I have been weened off everything.

Today, I went for my second appointment at Emeritus Research. I had pretty much written-off my weekend, just in case I had side effects from whichever drug they put me on but (please press)

Today I was shown how to use my electronic diary…and that’s it. How disappointing: I have to wait ‘til next week before I start whichever regime I have been randomly chosen to undertake. I will be (randomly) assigned to one of 4 groups: Placebo, 300mg Lyrica, 15mg Mirogabalin or 30mg Miroglabin. There will be regular check-ups for the entire time.

So, until next week…

NOTE: Emeritus Research is still recruiting for the study, if anybody is interested. Click for  the Consent Form and information. Contact Daiichi using this email address – SM_DS5565_FM_Info@incresearch.com.

As well as the 1000 person study in the US and Canada, Daiichi is also recruiting in:

  • Campse and Coffs Harbour, NSW, Australia;
  • Maroochydore, Sherwood and Southport, Queensland, Australia;
  • Hobart, Tasmania, Australia;
  • Malvern East, Victoria, Australia;
  • Tallin and Tartu, Estonia;
  • Baldone, Jekabpils, Liepaja, Ogre and Riga, Latvia;
  • Auckland, Hamilton, Nelson, Tauranga and Wellington, New Zealand;
  • Banska Bystrica, Bratislava and Dubnica Nad Vahom, Slovakia; and,
  • Reading, Berkshire; Chesterfield, Derbyshire; Wellingborough, Northamptonshire: Atherstone, Warwickshire; and
  • Belfast, United Kingdom.

strip

Round 2 – It’s a Knock Out.

Hey!

boxing-pills-supplements-sports-05102011Remember I just wrote about a current study run by Daiichi Sankyo, a Japanese drug company?

Have another look – see that I wrote about the drug trial underway in the U.S and Canada?

Guess what? I found out some more information!

The study is also recruiting in:

  • Campse and Coffs Harbour, NSW, Australia;
  • Maroochydore, Sherwood and Southport, Queensland, Australia;
  • Hobart, Tasmania, Australia;
  • Malvern East, Victoria, Australia;
  • Tallin and Tartu, Estonia;
  • Baldone, Jekabpils, Liepaja, Ogre and Riga, Latvia;
  • Auckland, Hamilton, Nelson, Tauranga and Wellington, New Zealand;
  • Banska Bystrica, Bratislava and Dubnica Nad Vahom, Slovakia; and,
  • Reading, Berkshire; Chesterfield, Derbyshire; Wellingborough, Northamptonshire: Atherstone, Warwickshire; and
    Belfast, United Kingdom.

Good luck, if you’ll be trying to get in.

Untitled

Gamechanger Going Viral

Over ten years of medical research has yielded some promising results – “It is a tip of the iceberg” – in terms of finding something to finally ease our battle with FM. Dr William “Skip” Pridgen has been researching FM for the past 15 years while simultaneously working in this full-time surgical practice, Tuscaloosa Surgical Associates PC. Through his research, he has developed a new drug and a treatment that may one day actually provide a cure for FM! IMCHis research has also led him to create Innovative Med Concepts, which is a new biotech company that one day hopes to bring forth the medical discoveries to the marketplace.

Currently there are various drugs that (supposedly) treat the symptoms of FM but there is no definitive cure. (Don’t we know it!)

Pridgen first got started with his while he was attempting to help his patients that were dealing with pain from irritable bowel syndrome. He had first discussed the problem with his mother, who is a biotechnologist at St. Jude’s Children’s Research Hospital in Memphis, Tennessee.  As the two continued to talk about the subject, they began to theorize that FM may be caused by a herpes virus that weakens one’s immune system. That was when Pridgen began extensively researching. Pridgen also states that he didn’t get serious about it until he had accompanied his daughter on a medical mission to Honduras. Pridgen’s daughter is fluent in Spanish, and she served as his translator in treating his patients. He learned that many of them were suffering extreme pain bought on by Fibromyalgia.

Pridgen says that seeing the suffering first hand of those Honduran patients drove him to devote more of his time to researching the condition. It also had meant working two jobs, medical researcher and surgeon.

a120707_BH_091_Duffy_Carol_and_Pridgen_Skip-300x199Pridgen, along with Carol Duffy, who holds a doctorate in virology as well as being an assistant professor of biological sciences at the University of Alabama, have together developed a drug that both believe will cure the problem. So far, two trial phases to test their new drug and treatment have yielded some incredibly promising results. Pridgen comments “We got 90% of the results back and they are very positive. In the next couple of weeks we will see all the data.” Both researchers hope to soon move on to the final phase of the testing, but that’s a process that could take several years. However, if the results from the trial phase prove to be successful, the United States FDA could approve the drug for widespread use in humans.

Pridgen says “We feel we are on the right track and feel this is a real game changer…What we are discovering will accomplish so much more.”

The third phase of testing will take approximately 2-3 years to complete and will start with a thorough toxicology study to make certain that the higher doses of the drug will be safe for the FM patients taking it. If the toxicology study results satisfy the FDA, they would give the OK to start testing.

Pridgen says “The ultimate goal if the drug succeeds will be to get people suffering the pain caused by Fibromyalgia back into the workforce and back to where they can enjoy life.” YIPPEE!!!


Int Fibro

Acoustic Brainwave Activation – Why is it Here?

Acoustic Brainwave ActivationYou may have noticed a new ad on the right hand side of the page for Acoustic Brainwave Activation. I haven’t tried it yet (I am totally broke) BUT it sounds really good (or am I being naïve?) so I have put it up as a trial – if any of you have had any experiences with the product, please write a comment below.

The company claims a multitude of fabulous ‘aids’ (I don’t think that’s the correct word but it will have to do for now) but I’m only going to look at the ones that may help us:

Chronic Fatigue

Using acoustic brainwave activation, Medipower are able to change the electrical activity in the brain and induce the correct delta frequencies and diminish the interfering alpha frequency incursions – It is delta wave sleep that is the “deepest” stage of sleep and the most restorative. It is delta sleep that a sleep-deprived person’s brain craves the first and foremost.

acoustic brainwave activationThe product directly addresses the issue of reaching the delta state early in your sleep cycle. It encourages this deep level of sleep in a gentle manner and allows the process of recovery and repair to begin. The program is 45 minutes long and should be listened to, in its entirety, when going to sleep.

As it does not require headphones to be effective it can be played on repeat or loop throughout the night if required.

It can also be used through the day to help with recovery and additional restful sleep.

Improving Memory

It has been proven beyond all reasonable doubt that short and long-term memory can be improved by relaxing and meditating in the alpha range. Stimulating a certain part of that alpha range with acoustic activation will increase this benefit even further. The improvement in memory will be rapid, consistent and permanent.

Stress Relief and Deep Relaxation

You are guided through gentle relaxation techniques to relieve tension. In a state of calm reverie, you enter an inner sanctuary, a magical garden that you can return to again and again to restore your sense of self. You will learn how to generate powerful states of being that will contribute to an ever-increasing sense of well-being in your life. At the end you re-emerge into the world cleansed, revitalized and ready to tackle any challenges with a fresh attitude.

All tracks are ideal for stress reduction or creative problem solving and allows you to unwind at your own pace. The gentle pulsations of soothing Alpha, Theta and Delta waves move your mind into a regenerative state of well-being. Your consciousness is lifted above fragmented thoughts and worries, becoming unified in peaceful repose. You experience a euphoric release from anything and everything that bothers you.

HypnoGuide treatments are the simplest and most affordable way to directly influence your inner potential and release the power of your subconscious mind! HypnoGuide treatments are also much more advanced than ordinary hypnosis or meditation CD´s being offered today. Nowhere else can you find recordings this long at this low price!

60-day-guarantee-money-back-smallLike many on-line sellers, there are plenty of products and packages available to purchase and download. AND, importantly, all are backed by a 60 day money back guarantee!

Meditation Power – Acoustic Brainwave Activation provides 7 days/24 hours/365 days online customer services. They have been around since 2007 and have received a number of very positive reviews:

reviewxrating3

review

So, after all that, I figured what have we got to lose? Let me know how you go…please.

try this
Int Fibro

New studies Find Causes of Fibromyalgia

Oh…LOOK! Two new studies on FM have ‘solved’ the on-going mystery that is FM. How many causes of this mystery is that, now?

thyroidThese studies focus the problem on the thyroid, pituitary and hypothalamus, and suggest new avenues of relief for sufferers.

Research from the FM Research Foundation reveals deficient thyroid hormone regulation (DTHR) as an underlying cause of FM. Poor diet, poor physical fitness and metabolism slowing drugs are primary contributors to symptoms as do additional hormonal imbalances of cortisol, estrogen and progesterone.

Another study, by Dr John Lowe, Diplomat of the American Academy of Pain Management and Director of Research at the FM Research Foundation in the UK claims “indisputable proof” that the primary cause of FM are with the pituitary gland or the hypothalamus.

The most often reported symptoms of FM so closely match with hypothyroidism that many physicians order a standard thyroid test in response to complaints from FM sufferers. When that test comes back negative, physicians dismiss a thyroid or hormonal disease.

Many of those tested show ‘thyroid anti-bodies’ with a normal TSH. The presence of anti-bodies indicates the thyroid is in the process auto-immune failure. However, because the TSH levels are normal, doctors do not prescribe medications.

Endocrinologists support treating the thyroid even if the TSH test is within normal range. The patient may present with symptoms of hypo-thyroidism, hyper-thyroidism or a flux of the two and often told they have FM.

The UK studies claim this description is, in fact, FM.

Many doctors do not understand this is a bell curve measurement and ‘normal’ may not mean ‘individual,’ and two different laboratories may indicate two separate results.

65. snowflakes

The words of Dr Elizabeth Vliet who runs a women’s health clinic art All Saints Hospital in Fort Worth TX and is the author of Screaming to be heard: Hormonal connections women Suspect and Doctors Ignore, seems to support the UK findings.

“The problem I have found is that too often women are told their thyroid is normal without having the complete thyroid test done. Of course, what most people and many physicians don’t realize is that a ‘normal range’ on a laboratory report is just that: a range.

A given person may require higher or lower levels to feel well and to function optimally. I think we must look at the lab test results along with the clinical picture described by the patient.

I have a series of more than 100 patients, all but two are women, who had a normal TSH and turned out to have significantly elevated thyroid anti-bodies that meant they needed thyroid medication in order to feel normal.

This type of oversight is particularly common with a disease call thyroiditis which is 25 times more common in females than males. A woman may experience symptoms of the disease for months to years before the TSH goes up.”

This fits with the UK research which states the condition may not rest with the thyroid but with the pituitary gland or the hypothalamus.

The UK research claims plausible evidence of at least 40 abnormalities of FM patients as a result of testing within range and show such symptoms as:

Widespread pain, tenderness, chronic fatigue, stiffness, depression, fuzzy brained, anxious, intolerance to cold , hot flashes (dependant) bowel issues, sleep disturbances, numbness and tingling, dry skin and mucus membranes, headaches and exercise intolerance-all hallmarks of FM.

Too little thyroid regulation also affects the metabolic aspects of FM and the UK studies concluded resting metabolic rates of those with undetected thyroid issues measured 29 percent lower than average.

Basal body temperature was 96.38. This lower core temperature combined with a poor resting metabolic rate can make an FM victim run the gamut in symptoms.

The new research provides hope for a cure for FM sufferers. The FM Research Foundation ran clinical trials with FM patients using thyroid hormone therapy without using the T4 hormone and found those in the controls groups that had FM improved substantially when re-tested one to five years after initial treatment.

The researchers claim “granite hard findings” for the cause of FM and the relief via treatment.

80. diet weekFM sufferers may benefit from consultations with a neuro – endocrinologist for diagnosis and treatment. An all-natural, reduced calorie diet along with moderate exercise is mandatory to diminish or eliminate symptoms. Analgesics and sleep medication may also help reduce the symptoms of FM (so they say this time!)

 

A Drink to Your Good Health

I have previously written about the first study to examine the association between alcohol consumption, symptom severity, and quality of life of individuals with FM. 103. drug comboTreatment of FM is challenging because the drug therapies currently available are expensive and associated with numerous undesirable (understatement) side effects and addiction or tolerance issues. Despite undergoing drug treatment, patients are often left with unrelieved pain, restricted mobility, and reduced physical function.

63. vegetables(Unfortunately for some) Lifestyle interventions, including dietary modifications such as alcohol consumption, have gained popularity as explorations in symptom management.

Several studies have examined the association between alcohol consumption and chronic pain conditions. In one study, regular weekly or daily alcohol consumption was shown to be a significant protective factor for the development of chronic pain. Two studies have also shown that moderate alcohol consumption correlates with a reduced risk of rheumatoid arthritis .

In this current study, researchers are the first to examine the association between alcohol consumption and FM symptom severity and quality of life. Among the 946 adult FM patients (94 % women, mean age of 49 years old) reporting low or moderate alcohol consumption (≤3 or >3 to 7 drinks per week), there was lower FM symptom severity and better quality-of-life scores compared with those who reported no alcohol consumption. However, these associations were not observed in patients who were heavy drinkers (>7 drinks per week) compared with non-drinkers. Drinkers had higher education, less unemployment, lower body mass index, and lower frequency of opioid use than non-drinkers. Thus, their analyses were adjusted for these potential confounders.

133. well behaved womenBecause alcohol consumption consists of complex behaviours that intersect with many social, economic, psychological, and demographic factors, disentangling this complex web of relationships is a challenge. Interestingly, after exploring possible mechanisms for their findings, the researchers speculated that alcohol consumption may reduce FM symptoms and improve quality of life by mediating psychological benefits and stress relief or by promoting factors associated with social integration. Another possible mechanism proposed is central nervous mediation via the modulating gamma-aminobutyric acid (GABA) system. Behavioural and pharmacological therapies that modulate or mimic the effects of GABA production can be promising for FM treatment.

This initial exploration into the relationships between alcohol consumption, symptom severity, and quality of life for FM has posed a number of questions that need to be answered by future studies with stronger study designs. There are limitations associated with cross-sectional study design: information bias is not uncommon in cross-sectional studies providing data on both exposure and outcome variables from questionnaires – questionnaires are administered at the same time in a cross-sectional study and rely on respondent recall, the measurement errors of exposure (ie, alcohol consumption) may be dependent on the measurement errors of the outcomes (ie, quality of life or FM symptoms). Where such dependent bias occurs, the association between exposure and outcome is likely to be inflated. This basically means that these preliminary results should not be used as grounds for advising patients to drink alcohol (Bummer!).

70. never aloneThis research sheds new light on plausible hypotheses and mechanisms to consider in future methodologically rigorous studies to improve the well-being of individuals with FM, but does not give us immediate relief.

Fibromyalgia Mystery Solved (Again!?!)

So, I was sent a link to an article which once again extolled the virtues of the FM mystery’s latest research:

66. Invisible IllnessResearchers have found the main source of pain in FM patients, and contrary to what many believe, it does not stem from the brain. The findings mark the end of a decades-old mystery about the disease, which many doctors believed was conjured in patients’ imaginations. Up until recently, many physicians thought that the disease was “imaginary” or psychological, but scientists have now revealed that the main source of pain stems from a most unlikely place – excess blood vessels in the hand.

The discovery may lead to new treatments and perhaps even a total cure in the future (?) To solve the mystery, researchers zeroed in on the skin from the hand of one patient who had a lack of the sensory nerve fibres, causing a reduced reaction to pain. They then took skin samples from the hands of FM patients and were surprised to find an extremely excessive amount of a particular type of nerve fibre called arteriole-venule (AV) shunts.

Up until this point scientists had thought that these fibres were only responsible for regulating blood flow, and did not play any role in pain sensation, but now they’ve discovered that there is a direct link between these nerves and the widespread body pain that we feel.

The breakthrough also could solve the lingering question of why many sufferers have extremely painful hands as well as other “tender points” throughout the body, and why cold weather seems to aggravate the symptoms.

In addition to feeling widespread deep tissue pain, most of us also suffer from debilitating fatigue.

Neuroscientist Dr Frank L. Rice explained: “We previously thought that these nerve endings were only involved in regulating blood flow at a subconscious level, yet here we had evidences that the blood vessel endings could also contribute to our conscious sense of touch… and also pain,” Rice said. “This mismanaged blood flow could be the source of muscular pain and achiness, and the sense of fatigue which are thought to be due to a build-up of lactic acid and low levels of inflammation. This, in turn, could contribute to the hyperactivity in the brain.”

216. capsulesCurrent treatments for the disease have not brought complete relief to the millions of sufferers. Therapies include narcotic pain medicines; anti-seizure drugs, anti-depressants and even simple advice such as “get more sleep and exercise regularly.”

Now that the cause has been pinpointed, patients are looking forward to an eventual cure. Others expressed frustration about how much they had suffered already: “When are they ever going to figure out that things are never “all in your head?” said one commenter.

“Whenever something doesn’t fit in their tiny little understanding, they belittle the patient and tell them they are crazy. People have suffered through this since they were invented. Prescribing SSRIs for everything is not the answer any more than a lobotomy or hysterectomy was.”

The announcement has the potential to unlock better future treatments and undoubtedly has patients all over the world rejoicing that the mystery of Fibromyalgia has finally been solved.

So…how many times have they solved(?) this mystery so far?